Impaired sensorimotor gating occurs in neuropsychiatric disorders such as schizophrenia and can be measured using the prepulse inhibition (PPI) paradigm of the acoustic startle response.This assay is frequently used to validate animal models of neuropsychiatric disorders and to explore the therapeutic potential of new drugs.The underlying neural ne
Outcomes of limited stage primary bone diffuse large B-cell lymphoma in the rituximab era: a multicenter, retrospective study
Primary bone diffuse large B-cell lymphoma is a rare variant of extranodal non-Hodgkin lymphoma historically treated with induction chemotherapy followed by consolidative radiation therapy (RT).It remains unknown whether RT confers additional benefit following rituximab-based chemoimmunotherapy (CIT) induction in patients with limited stage disease
Timing Of Primary Surgery for cleft palate (TOPS): protocol for a randomised trial of palate surgery at 6 months versus 12 months of age
Introduction Cleft palate is among the here most common birth abnormalities.The success of primary surgery in the early months of life is crucial for successful feeding, speech, hearing, dental development and facial growth.Over recent decades, age at palatal surgery in infancy has reduced.This has led to palatal closure in one-stage procedures bei